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Expand samples. Break imaging barriers. Reveal untapped insights.

Expand samples. Break imaging barriers. Reveal untapped insights.

Streamlined expansion tools and services that empower researchers and labs to quickly master complex nano-scale imaging with ease.

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About Magnify™

Illuminating the path to precision medicine with beyond-limit imaging.

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Our Products

Entrusted by more than 150+ research institutes and biotech/biopharma companies worldwide, Magnify Biosciences is simplifying the path to super-resolution imaging.

Our Magnify™ Kit provides a user-friendly, rapid solution that enables researchers to quickly adopt Magnify™ Expansion Microscopy without the need for complex and time-consuming method development. The kit features a proprietary hydrogel chemistry that immobilizes various biomolecules for precise, isotropic expansion. Validated across multiple sample and tissue types and manufactured under rigorous quality control, Magnify™ brings cutting-edge nanoscale analysis to your lab with confidence and ease.

Ready to see the unseen? Enjoy a one-time 25% discount (excluding shipping) on your first kit with coupon code FIRSTTIME.

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Our Services

Partnering with a diverse range of clients, from top 20 global biopharma giants to agile biotech startups, Magnify™ Biosciences accelerates pre-clinical drug development and disease research. We provide a uniquely collaborative, end-to-end service, from expert specimen preparation to advanced nanoimaging and data analysis.

What truly sets us apart are our interactive, real-time nanoimaging sessions. Go beyond static reports and engage in direct discussion with our experts as we explore your data together. This hands-on approach to mapping the molecular organization of disease biomarkers and biologics at a sub-organelle scale empowers your team to make faster, more informed decisions.

Reach out for more information to discuss how our services can advance your research program!

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Why Magnify™

Magnify™ expand the horizon of your microscope

Blog & News

The Future of Imaging is Here

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Magnify™ Biosciences Featured in FluoroFinder’s Latest Article on Multiplexed Immunofluorescence

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Magnify™ Biosciences Inc. Featured in Nature for Advancing Expansion Microscopy!

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Read More News & Blogs

Supported By

Allegheny Health Network
Alphalab Health
Cincinnati Children's Hospital
CMU
Innovation Works
LifeX
NIH
NSF
University of Cape Town
UPMC

Testimonials

With Magnify™, we’ve bypassed the tedious method development stage when adopting expansion microscopy in our lab. This has allowed us to achieve exciting results for our publication in a fraction of the time, enabling us to visualize nanoscale structures that were previously inaccessible, with the precision and resolution needed for our specific research goals.
Dr. Yang LiuProfessor, Beckman Institute, UNIVERSITY OF ILLINOIS URBANA-CHAMPAIGN
Magnify's kit has been a game-changer for our fast-paced imaging core facility. It equips our faculty with the tools to efficiently perform state-of-the-art Expansion Microscopy, adding a powerful option to their imaging toolbox.

The Magnify™ hydrogels are sturdier and easier to handle than those from our older ExM protocols, and the properly QCd reagents ensure reproducible polymerization under a variety of conditions. This eliminates the need to second-guess reagent viability before starting experiments. The simple kit chemistry allows users from diverse backgrounds and expertise to successfully prepare samples using Expansion Microscopy. We’re pleased to have saved both time and effort, avoiding the need to reinvent the wheel.
Dr. Matthew KofronDirector, Bio-Imaging and Analysis Facility, Cincinnati Children's Hospital Medical Center
Magnify’s technical team collaborates closely with us, not just to solve challenges, but to customize solutions that align with our specific research goals. This partnership has been especially valuable in navigating complex and less-defined projects, making Magnify™ a dependable partner in achieving successful outcomes, regardless of the research challenges.
Dr. Bo JingVP Genome Design, Replay Bio
Having worked with various expansion methods, I find Magnify’s kit exceptional in streamlining multiple steps while delivering consistently excellent results, even with complex samples like Drosophila ovaries. The user-friendly design, handy small tools, and clear procedural visuals, along with comprehensive video tutorials, make the expansion process much easier—even for seasoned users. We achieved proportional and reproducible expansions, successfully completing both 4x and 16x expansions. I particularly appreciate how the kit reduces time and effort while offering the flexibility needed for customization, allowing us to focus more on advancing our research.
Dr. Mariana De NizNikon Imaging Center Manager, Northwestern University
Magnify's kits have been very useful to our imaging core facility at a medical center. Previous attempts at expansion techniques were challenging due to inconsistent chemical purity, but the Magnify™ kits produce stable, easy-to-handle, and reproducible gels. The kits enable efficient, replicable Expansion Microscopy, adding a powerful tool for our research. The ability to expand without disruptive protease digestion, perform post-homogenization staining for brighter target signals, and streamline the process by eliminating separate anchoring steps allows for the simultaneous imaging of multiple biomolecule types. Customizable kits tailored to user needs have further minimized troubleshooting and made replicable expansions straightforward.
Amanda RaineyBio-Imaging and Analysis Facility, Cincinnati Children's Hospital Medical Center

Publications

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Z. Cheng, C. Stefani, T. Skillman, A. Klimas, A. Lee, E. DiBernardo, K. Brown, T. Milman, Y. Wang, B. Gallagher, K. Lagree, B. Jena, J. Pulido, A. Mitchell, S. Filler, L. Hiller, A. Lacy-Hulbert, Y. Zhao*, “MicroMagnify: a multiplexed expansion microscopy method for pathogens and infected tissues”, Advanced Science, 2023, 2302249.

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A. Klimas, B. Gallagher, P. Wijesekara, S. Fekir, E. F. DiBernardo, Z. Cheng, D. Stolz, F. Cambi, S. Watkins, S. L. Brody, A. Horani, A. L. Barth, C. Moore, X. Ren, Y. Zhao*, “Magnify is a universal molecular anchoring strategy for expansion microscopy”.Nature Biotechnology 41, pages 858–869 (2023).

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F. Han, S. Gu, A. Klimas, N. Zhao, Y. Zhao* (co-corresponding), S-C, Chen*, “Three-dimensional nanofabrication via ultrafast laser patterning and kinetically regulated material assembly”, Science, 2022, 378, 6626

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L. Shi, A. Klimas, B. Gallagher, Z. Cheng, F. Fu, P. Wijesekara, Y. Miao, X. Ren, Y Zhao* (co-corresponding author), W Min*, “Super-resolution vibrational imaging using expansion stimulated Raman scattering microscopy”, Advanced Science,2022, 2200315.

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A. Abdelfattah, S. Ahuja, T. Akkin, S.R. Allu, D.A. Boas, J. Brake, E.M. Buckley, …, Y. Zhao, “Neurophotonic tools for microscopic measurements and manipulation: status report”,Neurophotonics 9 (S1), 013001

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